Bone markers after total body irradiation in childhood
نویسندگان
چکیده
منابع مشابه
Hyperparathyroidism in Survivors of Childhood Malignancy after Total Body Irradiation
Objective: The risk of developing hyperparathyroidism (HPT) in adults after radiation exposure is higher than that of the general population. Extensive follow up guidelines of United Kingdom Children’s Cancer Study group (UKCCSG) or Scottish intercollegiate guidelines network (SIGN) do not recommend monitoring serum calcium or parathyroid hormone in patients treated for childhood malignancies. ...
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Total-body irradiation (TBI), when given as part of bone marrow transplantation (BMT), works by enhancing immune suppression and by exerting a tumoricidal effect. The modality has been made less toxic because of new approaches to delivering TBI, such as fractionation, and partial organ shielding, Colleen Lawton, MD, professor at the Medical College of Wisconsin, Milwaukee, said at the 1998 Amer...
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Endocrine function was assessed in 31 children (17 boys) after fractionated total body irradiation used in the preparative regimen for bone marrow transplantation. Endocrine dysfunction was present in 25 children. Fifteen of 29 had growth hormone insufficiency 0.9-4.9 years after total body irradiation, yet only three of the 15 had received previous cranial irradiation. Five of 30 had thyroid d...
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criteria and 40% in the best schedule (5-day intravenous). This compares favorably with prior experiences with decitabine and 5-azacitidine (CR rates, 6%-20%).4,5 Also, decitabine was less toxic than 5-azacitidine in relation to nausea/vomiting and local skin reactions (pain and induration in 5%-10% of patients on 5-azacitidine). The incidence of 65% of hospitalization is cumulative. As one del...
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Two children developed papillary thyroid carcinoma after allogeneic bone marrow transplantation (BMT) probably due to radiotherapy during remission and pretransplantation conditioning. Establishing a relationship between the cellular thyroid stimulating hormone (TSH) effect and development of carcinoma in cases with high serum TSH concentrations is difficult. After BMT, patients should be regul...
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ژورنال
عنوان ژورنال: Bone Marrow Transplantation
سال: 2009
ISSN: 0268-3369,1476-5365
DOI: 10.1038/bmt.2009.198